I don't know if this is a best hole, but it's a hard fucker.
#3 at Hidden Acres in Beatrice. 421 yard par 4, OB left, Creek right, creek @ 208, Creek at 295. Tight as shit sloped fairway. Big motherfucking tree that overhangs in the fairway at the creek @ 295.
It used to be like the 3rd hardest hole in Nebraska 15-20 years ago. But it's a real bitch. If you can rope a baby draw to about 265-275 without going OB, you'll be left with a baby cut of about 175 around this big fucking tree. It's a challenge.
Side note, I won a 1 man scramble there by parring that fucker by ripping a punch basically through the bridge over the 2nd creek.